Medical
Developing a low-cost finger-prick sensor for blood potassium levels
Contact: Dr Tanya Hutter, Chemistry Mentor: Tom Collings, Cambridge Consultants Maintenance of blood potassium levels within defined limits is crucial to health; healthy blood potassium levels are between 3.5 and 5.0 mmol/L. Both severe hyperkalaemia (high-potassium) and hypokalaemia (low-potassium) are associated with abnormal heart rhythms and sudden death. In patients with kidney dysfunction, potassium levels…
Novel extraction of specialist cells for use in cellular therapeutics
Contact: Dr. Krishnaa Mahbubani & Dr. Kourosh Saeb-Parsy, Department of Surgery Mentor: Dr. Karin Schmitt Human peripheral blood mononuclear cells (PBMCs) isolated from living donors are the main source of lymphocytes for basic and translational research, including drug screening and the generation of cellular immunotherapies such as Chimeric Antigen Receptor (CAR) and regulatory T cells.…
Investigating the best routes to market for MyICUVoice – an
Contacts: Dr. Tim Baker, Speciality Registrar & Dr. Vilas Navapurkar, Consultant in Intensive Care, Addenbrooke’s Hospital Mentor: Clara Aranda-Jan Admission onto an intensive care unit (ICU) is one of the most frightening lifetime experiences a patient or their relative can have. Research has shown that an inability to communicate is the most distressing and frustrating…
Developing the first diagnostic test for neurodegenerative diseases before the
Contact: Professor David Klenerman FRS, Dr. Steven F. Lee, Dr. Mathew H. Horrocks, Chemistry Diagnosis of neurodegenerative diseases such as Parkinson’s Disease and Alzheimer’s Disease can only be done definitively by post-mortem analysis of the brain. Since the brain compensates for damage, clinical symptoms will typically only appear when as much as 70% of the brain…